ACAI serves as a regional hub for generating and disseminating profound knowledge on active ageing. It aims to establish a centralised knowledge hub to facilitate regional learning, showcase successful case studies, and inspire the replication of best practices across ASEAN Member States (AMS).

The Centre focuses on translating global and regional frameworks into evidence-informed national policies and actionable strategies. By advocating for multi-sectoral integration and providing technical guidance, ACAI helps AMS align their ageing policies with national development priorities and the ASEAN Post-2015 Health Development Agenda.

ACAI implements capacity development initiatives, including training for country coordinators, policymakers, and practitioners. These programs utilise workshops, webinars, and field visits to equip stakeholders with the tools necessary to implement community-based care models and promote digital inclusion for older persons.

ACAI conducts research and development that translates scientific findings into actionable, system-oriented strategies. A core component of this mission is the launch of joint research and implementation programs designed to address regional ageing challenges and establishes a robust research network and collaboration framework.

The Centre plays a critical role in tracking the region's advancement through the development of the ASEAN Active Ageing Index (AAAI). ACAI ensures systematic progress tracking and delivers assessment reports to stakeholders to ensure accountability and impactful results.